Primary Identifier | MGI:106013 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 20501 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables lactate transmembrane transporter activity. Involved in several processes, including plasma membrane lactate transport; pyruvate catabolic process; and regulation of insulin secretion. Located in plasma membrane. Is active in synapse. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 7. Orthologous to human SLC16A1 (solute carrier family 16 member 1). PHENOTYPE: Homozygotes are non-viable, while heterozygous animals are resistant to diet-induced obesity. [provided by MGI curators] |