| Primary Identifier | MGI:106028 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 11853 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Involved in apical junction assembly and positive regulation of protein-containing complex assembly. Located in nucleus; plasma membrane; and stereocilium. Is expressed in hippocampus. Orthologous to human RHOC (ras homolog family member C). PHENOTYPE: Homozygous null mutation in this gene results in no abnormal phenotype, except for reduced stress fiber formation in serum starved fibroblasts. However, in combination with Tg(MMTV-PyVT)634Mul mice, metastatic potential of tumors and tumor cell motility are decreased. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
