| Primary Identifier | MGI:1914421 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 67171 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Involved in photoreceptor cell maintenance. Acts upstream of or within cell population proliferation; phloem or xylem histogenesis; and retina development in camera-type eye. Located in apical plasma membrane and photoreceptor inner segment. Is expressed in several structures, including alimentary system; eye; genitourinary system; hemolymphoid system gland; and nervous system. Used to study cone-rod dystrophy. Human ortholog(s) of this gene implicated in cone-rod dystrophy. Orthologous to human DRAM2 (DNA damage regulated autophagy modulator 2). PHENOTYPE: Homozygous null mice show age-related photoreceptor degeneration starting at 18 months of age without impacting visual function. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
