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Protein Coding Gene : Amigo1 adhesion molecule with Ig like domain 1

Primary Identifier  MGI:2653612 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  229715
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables potassium channel regulator activity. Involved in positive regulation of potassium ion transmembrane transport. Acts upstream of or within positive regulation of synapse assembly. Located in dendrite and neuronal cell body membrane. Part of voltage-gated potassium channel complex. Is expressed in several structures, including branchial arch; central nervous system; genitourinary system; gut; and sensory organ. Orthologous to human AMIGO1 (adhesion molecule with Ig like domain 1).
PHENOTYPE: Mice homozygous for a null allele show a reduced size of retinal horizontal cell axons with no changes in the size of their dendrites or the ability of both arbors to form connections. The changes in horizontal cell axons are matched by changes in synaptic partner dendrites to stabilize retinal function. [provided by MGI curators]
  • synonyms:
  • adhesion molecule with Ig like domain 1,
  • Amigo1

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

2 Driver For