| Primary Identifier | MGI:1858235 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 53883 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G protein-coupled receptor activity and calcium ion binding activity. Involved in several processes, including Wnt signaling pathway; homophilic cell adhesion via plasma membrane adhesion molecules; and neural plate anterior/posterior regionalization. Acts upstream of or within several processes, including cerebrospinal fluid secretion; cilium assembly; and nervous system development. Located in cytoplasm and plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; skin; and visual system. Used to study hydrocephalus. Orthologous to human CELSR2 (cadherin EGF LAG seven-pass G-type receptor 2). PHENOTYPE: Mice homozygous for disruptions in this allele have mild to moderately dilated lateral ventricles in the brain but are otherwise normal. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
