| Primary Identifier | MGI:102809 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 20226 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including aminoacyl-tRNA ligase activity; nucleic acid binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including negative regulation of angiogenesis; negative regulation of macromolecule biosynthetic process; and translation. Located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; exocrine system; and genitourinary system. Human ortholog(s) of this gene implicated in intellectual disability. Orthologous to human SARS1 (seryl-tRNA synthetase 1). PHENOTYPE: Mice homozygous for a knock-out allele show complete embryonic lethality before implantation with abnormal morula morphology, increased cell death, and failure of blastocyst formation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
