| Primary Identifier | MGI:1927653 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 64378 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables cytoskeletal motor activity. Involved in motor learning. Acts upstream of or within locomotory behavior; neuromuscular process controlling balance; and neuronal action potential. Predicted to be located in ciliary membrane; cytoplasm; and nucleus. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; ear; genitourinary system; nervous system; and skeleton. Orthologous to human GPR88 (G protein-coupled receptor 88). PHENOTYPE: Mice homozygous for a null allele show enhanced medium spiny neuron activity, hyperactivity, impaired motor coordination, and altered motor- and cue-based learning. Homozygotes for a different null allele show a motor skill deficit, enhanced spatial learning, stereotypies, and lower anxiety levels. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
