Primary Identifier | MGI:1913618 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 66368 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable RNA-3'-phosphate cyclase activity. Involved in negative regulation of optical nerve axon regeneration. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in dorsal root ganglion; retina; and retina ganglion cell layer. Orthologous to human RTCA (RNA 3'-terminal phosphate cyclase). PHENOTYPE: Mice homozygous for a hypomorphic allele exhibit incomplete prenatal lethality and enhanced retinal ganglion cell axon regeneration after optic nerve crush injury. [provided by MGI curators] |