Primary Identifier | MGI:1923019 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 75769 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable phosphatidate phosphatase activity. Involved in positive regulation of filopodium assembly and positive regulation of neuron projection development. Located in plasma membrane. Is expressed in brain and cerebellum. Orthologous to human PLPPR5 (phospholipid phosphatase related 5). PHENOTYPE: Mice homozygous for a null allele exhibit increased susceptibility to hypoxia-ischemia injury and decreased responsiveness to melatonin treatment. [provided by MGI curators] |