Primary Identifier | MGI:1918731 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 71481 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable monosaccharide binding activity and protein serine/threonine kinase activity. Involved in cytoplasmic pattern recognition receptor signaling pathway and innate immune response. Acts upstream of or within response to bacterium. Located in photoreceptor connecting cilium. Orthologous to human ALPK1 (alpha kinase 1). PHENOTYPE: Homozygosity for the p.T237M mutation leads to increased levels of certain chemokines. [provided by MGI curators] |