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Protein Coding Gene : Gbp2b guanylate binding protein 2b
Primary Identifier  MGI:95666 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  14468
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables GMP binding activity and GTPase activity. Involved in cytolysis in another organism; positive regulation of defense response; and response to bacterium. Acts upstream of or within adhesion of symbiont to host; cellular response to interferon-beta; and defense response to other organism. Located in cytoplasmic vesicle and symbiont-containing vacuole membrane. Orthologous to several human genes including GBP2 (guanylate binding protein 2).
PHENOTYPE: Mice homozygous for a targeted allele exhibit increased susceptibility to bacterial infection. [provided by MGI curators]
  • synonyms:
  • Gbp-1,
  • macrophage activation 1,
  • MGD-MRK-12402,
  • Gbp1,
  • Mpa1,
  • MGI:97071,
  • guanylate binding protein 1,
  • MGD-MRK-12400,
  • MGD-MRK-10008,
  • guanylate binding protein 2b,
  • Mpa-1,
  • Gbp2b,
  • MGD-MRK-10009,
  • Mag-1,
  • LIMIT
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Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

Trail: ProteinCodingGene

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For





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