| Primary Identifier | MGI:1891916 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 56711 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of gene expression; positive regulation of gene expression; and positive regulation of glial cell proliferation. Acts upstream of or within gland morphogenesis and prostate gland growth. Predicted to be located in centrosome; cytosol; and nuclear speck. Is expressed in several structures, including central nervous system; embryo ectoderm; genitourinary system; limb bud; and sensory organ. Human ortholog(s) of this gene implicated in Silver-Russell syndrome and pleomorphic adenoma. Orthologous to human PLAG1 (PLAG1 zinc finger). PHENOTYPE: Homozygous null mice display reduced male fertility, small seminal vesicles and ventral prostate, reduced litter size (females only), reduced embryonic and postnatal growth, and delayed eyelid opening. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
