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Protein Coding Gene : Otud6b OTU domain containing 6B

Primary Identifier  MGI:1919451 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  72201
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in several processes, including proteasome assembly; protein deubiquitination; and regulation of translation. Predicted to be part of eukaryotic translation initiation factor 4F complex. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and liver and biliary system. Orthologous to human OTUD6B (OTU deubiquitinase 6B).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit complete perinatal lethality, decreased fetal size, and ventricular septal defects. [provided by MGI curators]
  • synonyms:
  • OTU domain containing 6B,
  • 2600013N14Rik,
  • RIKEN cDNA 2600013N14 gene,
  • expressed sequence AU015433,
  • AU015433,
  • Otud6b,
  • MGI:2140427

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Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Gene --> Protein-Protein Interactions

Expression

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Disease

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