Primary Identifier | MGI:2154278 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 140577 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable chloroplast targeting sequence binding activity. Acts upstream of or within negative regulation of canonical Wnt signaling pathway and positive regulation of Wnt signaling pathway, planar cell polarity pathway. Located in cytoplasm and nucleus. Is expressed in several structures, including jaw; nervous system; nose; orbito-sphenoid; and thymus primordium. Orthologous to human ANKRD6 (ankyrin repeat domain 6). PHENOTYPE: Mice homozygous for a null mutation display sporadic disruption of utricle hair cell polarity but normal cochlear and vestibular hair cell morphology. [provided by MGI curators] |