| Primary Identifier | MGI:99605 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 12804 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ciliary neurotrophic factor receptor activity. Acts upstream of or within several processes, including ciliary neurotrophic factor-mediated signaling pathway; negative regulation of motor neuron apoptotic process; and suckling behavior. Predicted to be located in apical plasma membrane. Predicted to be part of CNTFR-CLCF1 complex and ciliary neurotrophic factor receptor complex. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including central nervous system; lung; metanephros; sensory organ; and skeletal musculature. Orthologous to human CNTFR (ciliary neurotrophic factor receptor). PHENOTYPE: Homozygous mutant animals exhibit a significant reduction in the number of motor neurons. Neonatal mutants fail to suckle and die within 24 hours after birth. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
