| Primary Identifier | MGI:1342278 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 22249 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GTP-dependent protein binding activity; calmodulin binding activity; and syntaxin-1 binding activity. Involved in several processes, including positive regulation of defense response to bacterium; regulated exocytosis; and regulation of synaptic plasticity. Acts upstream of or within chemical synaptic transmission; innervation; and neuromuscular junction development. Located in several cellular components, including early phagosome; presynaptic active zone; and ribbon synapse. Is active in calyx of Held; glutamatergic synapse; and hippocampal mossy fiber to CA3 synapse. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and respiratory system. Orthologous to human UNC13B (unc-13 homolog B). PHENOTYPE: Homozygous mutant mice are grossly phenotypically normal. Mice older than 12 months will exhibit sporadic seizures. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
