| Primary Identifier | MGI:1889342 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 54390 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable kinase binding activity. Predicted to be involved in regulation of T cell activation. Predicted to be active in plasma membrane. Orthologous to human SIT1 (signaling threshold regulating transmembrane adaptor 1). PHENOTYPE: Homozygous null mice exhibit altered T-cell development, thymus hyperplasia, decreased lymph node cellularity and are more susceptible to develop experimental autoimmune encephalomyelitis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
