Primary Identifier | MGI:1916167 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 68917 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable adenosine 5'-monophosphoramidase activity. Acts upstream of or within lipid catabolic process and negative regulation of peptidyl-lysine acetylation. Located in mitochondrion. Is active in mitochondrial matrix. Is expressed in several structures, including brown fat; liver; lung; metanephros; and spleen. Orthologous to human HINT2 (histidine triad nucleotide binding protein 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit alterations in lipid metabolism, glucose homeostasis, and mitochondrial respiration. [provided by MGI curators] |