| Primary Identifier | MGI:1918656 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 71406 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in cellular response to amino acid stimulus; negative regulation of TORC1 signaling; and regulation of skeletal muscle tissue regeneration. Predicted to be located in late endosome membrane and lysosomal membrane. Predicted to be part of lysosomal proton-transporting V-type ATPase complex. Is expressed in several structures, including central nervous system; dorsal root ganglion; and sensory organ. Orthologous to human SPAAR (small regulatory polypeptide of amino acid response). PHENOTYPE: Mice homozygous for a knock-out allele are viable and grossly normal but exhibit improved skeletal muscle regeneration following cardiotoxin-induced muscle injury. [provided by MGI curators] |