| Primary Identifier | MGI:1933206 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 242443 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables NMDA glutamate receptor activity; calcium channel activity; and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Involved in presynaptic modulation of chemical synaptic transmission. Acts upstream of or within calcium ion transport; dendrite development; and prepulse inhibition. Located in neuronal cell body and postsynaptic membrane. Is active in glutamatergic synapse and postsynaptic density membrane. Is expressed in several structures, including adrenal gland; alimentary system; central nervous system; foot bone; and hand mesenchyme. Orthologous to human GRIN3A (glutamate ionotropic receptor NMDA type subunit 3A). PHENOTYPE: Mice homozygous for a disruption in this gene display increased current densities in some cerebrocortical neurons of the brain, increased levels of prepulse inhibition, and altered dendritic spine morphology. Otherwise, they display a normal phenotype. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
