| Primary Identifier | MGI:107171 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 19059 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables calcium-dependent protein serine/threonine phosphatase regulator activity. Acts upstream of or within penetration of zona pellucida. Located in sperm mitochondrial sheath. Part of calcineurin complex. Is expressed in several structures, including brain; lung; male reproductive gland or organ; renal vasculature; and upper jaw molar. Orthologous to human PPP3R2 (protein phosphatase 3 regulatory subunit B, beta). PHENOTYPE: Mice homozygous for a knock-out allele exhibit male infertility due to reduced hyperactivated sperm motility and midpiece rigidity. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
