| Primary Identifier | MGI:1333843 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 20529 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables copper ion transmembrane transporter activity; silver ion transmembrane transporter activity; and xenobiotic transmembrane transporter activity. Involved in angiogenesis; transition metal ion transport; and xenobiotic transport. Acts upstream of or within establishment of localization in cell and intracellular copper ion homeostasis. Located in several cellular components, including basolateral plasma membrane; endosome; and intercalated disc. Is expressed in several structures, including adrenal gland; alimentary system; early embryo; genitourinary system; and nervous system. Orthologous to human SLC31A1 (solute carrier family 31 member 1). PHENOTYPE: Mice homozygous for a null allele exhibit embryonic lethality during organogenesis associated with abnormal embryogenesis. Mice heterozygous for a null allele exhibit decreased copper levels in the blood and several organs. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
