| Primary Identifier | MGI:88002 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 11699 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including IgA binding activity; chondroitin sulfate binding activity; and collagen fibril binding activity. Predicted to be involved in several processes, including cellular oxidant detoxification; cytochrome c metabolic process; and hemoglobin metabolic process. Predicted to act upstream of or within protein maturation. Located in collagen-containing extracellular matrix. Is expressed in several structures, including brain meninges; gut; liver; metanephros; and umbilical artery. Human ortholog(s) of this gene implicated in acute kidney failure and adult respiratory distress syndrome. Orthologous to human AMBP (alpha-1-microglobulin/bikunin precursor). PHENOTYPE: Female homozygotes for targeted null mutations exhibit reduced ovulation rates, oocytes lacking a zona pellucida, and a very low fertilization rate. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
