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Protein Coding Gene : Tnfsf8 tumor necrosis factor (ligand) superfamily, member 8
Primary Identifier  MGI:88328 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  21949
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable cytokine activity and tumor necrosis factor receptor binding activity. Acts upstream of or within CD8-positive, alpha-beta T cell differentiation; defense response to Gram-positive bacterium; and positive regulation of transcription by RNA polymerase II. Predicted to be located in extracellular space and membrane. Is expressed in renal vasculature. Orthologous to human TNFSF8 (TNF superfamily member 8).
PHENOTYPE: Homozygous null mice diplay decreased susceptibility to graft versus host disease. [provided by MGI curators]
  • synonyms:
  • tumor necrosis factor (ligand) superfamily, member 8,
  • CD30 antigen ligand,
  • Cd30l,
  • CD153,
  • CD30LG,
  • MGD-MRK-1847,
  • Cd30L,
  • Tnfsf8
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Canonical gene --> Exons in specific strains

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Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

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4 Pathways

Trail: ProteinCodingGene

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Expression

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Phenotype

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Disease

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