| Primary Identifier | MGI:97479 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 18491 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables endopeptidase activity. Predicted to be involved in several processes, including protein catabolic process; proteolysis; and response to dexamethasone. Located in extracellular space. Is expressed in several structures, including central nervous system; genitourinary system; gut; limb; and paraxial mesenchyme. Human ortholog(s) of this gene implicated in myocardial infarction. Orthologous to human PAPPA (pappalysin 1). PHENOTYPE: Mice homozygous for a knock-out allele are viable but display decreased birth body size, delayed bone ossification, and proportional dwarfism. Female mice exhibit reduced fertility with decreased litter size and compromised ovarian steroidogenesis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
