Primary Identifier | MGI:2443805 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 242509 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables rDNA binding activity. Acts upstream of or within several processes, including endochondral bone growth; roof of mouth development; and tongue development. Located in chromatin and nucleus. Is expressed in several structures, including genitourinary system; jaw; nervous system; nose; and skin. Orthologous to human BNC2 (basonuclin zinc finger protein 2). PHENOTYPE: Mice homozygous for a gene trap insertion die within 24 hrs of birth and display cleft palate, an overall size reduction of the head and tongue, and abnormal craniofacial bone development due to impaired multiplication of embryonic craniofacial mesenchymal cells. [provided by MGI curators] |