Primary Identifier | MGI:2667156 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 230405 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cytokine activity and type I interferon receptor binding activity. Involved in defense response to bacterium and defense response to virus. Predicted to be active in extracellular space. Is expressed in diencephalon floor plate and midbrain floor plate. Orthologous to human IFNE (interferon epsilon). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased susceptibility to HSV-2 and Chlamydia infection. [provided by MGI curators] |