| Primary Identifier | MGI:1914263 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 67013 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables metalloendopeptidase activity. Involved in several processes, including diet induced thermogenesis; negative regulation of mitochondrial fusion; and protein processing. Acts upstream of or within cristae formation. Located in mitochondrial inner membrane. Is expressed in alimentary system; cerebral cortex; liver lobe; nose; and submandibular gland primordium. Orthologous to human OMA1 (OMA1 zinc metallopeptidase). PHENOTYPE: Mice homozygous for a targeted allele exhibit increased susceptibility to diet-induced obesity and defective thermogenesis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
