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Protein Coding Gene : Acot11 acyl-CoA thioesterase 11
Primary Identifier  MGI:1913736 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  329910
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable long-chain fatty acyl-CoA hydrolase activity. Involved in negative regulation of cold-induced thermogenesis and response to cold. Predicted to be located in mitochondrial matrix. Predicted to be active in cytosol. Orthologous to human ACOT11 (acyl-CoA thioesterase 11).
PHENOTYPE: Mice homozygous for a null mutation display resistance to high fat diet induced obesity, inflammation and hepatic steatosis, increased energy expenditure, increased brown adipose tissue amount, and increased food intake. [provided by MGI curators]
  • synonyms:
  • Acot11,
  • expressed sequence AW060409,
  • acyl-CoA thioesterase 11,
  • 1110020M10Rik,
  • mKIAA0707,
  • MGC:25974,
  • MGI:2140551,
  • BFIT1,
  • MGI:1915900,
  • RIKEN cDNA 2010309H15 gene,
  • Them1,
  • AW060409,
  • 2010309H15Rik,
  • Thea,
  • RIKEN cDNA 1110020M10 gene,
  • thioesterase, adipose associated
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4 Involved In Mutations

Trail: ProteinCodingGene

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

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Proteins

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Function

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Homology

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Interactions

4 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

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