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Protein Coding Gene : Nasp nuclear autoantigenic sperm protein (histone-binding)
Primary Identifier  MGI:1355328 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  50927
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables histone binding activity and histone chaperone activity. Involved in G1/S transition of mitotic cell cycle and blastocyst development. Acts upstream of or within DNA replication-dependent chromatin assembly. Located in cytoplasm and nucleus. Is expressed in several structures, including brain; extraembryonic component; heart ventricle; lung; and metanephros. Orthologous to human NASP (nuclear autoantigenic sperm protein).
PHENOTYPE: Mice homozygous for a null mutation display embryonic lethality before implantation. [provided by MGI curators]
  • synonyms:
  • Nasp-T,
  • 5033430J04Rik,
  • D4Ertd767e,
  • MGI:1289187,
  • Epcs32,
  • DNA segment, Chr 4, ERATO Doi 767, expressed,
  • nuclear autoantigenic sperm protein (histone-binding),
  • MGI:2140195,
  • AI317140,
  • expressed sequence AI317140,
  • expressed sequence AI131596,
  • MGI:2145613,
  • RIKEN cDNA 5033430J04 gene,
  • Nasp,
  • MGI:1914654,
  • AI131596
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Trail: ProteinCodingGene

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