| Primary Identifier | MGI:1921054 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 73804 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ATP hydrolysis activity; microtubule motor activity; and microtubule plus-end binding activity. Involved in postsynaptic cytoskeleton organization and regulation of neurotransmitter receptor localization to postsynaptic specialization membrane. Located in chromosome, centromeric region. Is active in glutamatergic synapse; postsynapse; and presynapse. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and sensory organ. Orthologous to human KIF2C (kinesin family member 2C). PHENOTYPE: Mice homozygous for a conditional allele activated in nerve cells exhibit reduced mushroom spine density, increased AMPAR-mediated EPSCs with increased surface AMPAR receptors, reduced freezing in response to context or tone conditioned stimulus, reduced investigation of a novel stranger, and impaired spartial working memory. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
