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Protein Coding Gene : Dph2 DPH2 homolog
Primary Identifier  MGI:1914978 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  67728
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable 4 iron, 4 sulfur cluster binding activity. Predicted to contribute to 2-(3-amino-3-carboxypropyl)histidine synthase activity. Predicted to be involved in protein histidyl modification to diphthamide. Part of 2-(3-amino-3-carboxypropyl)histidine synthase complex. Is expressed in liver lobe. Human ortholog(s) of this gene implicated in diphthamide deficiency syndrome 2. Orthologous to human DPH2 (diphthamide biosynthesis 2).
  • synonyms:
  • Dph2l2,
  • DPH2 homolog,
  • diptheria toxin resistance protein required for diphthamide biosynthesis (Saccharomyces)-like 2,
  • RIKEN cDNA 9130020C19 gene,
  • expressed sequence AI467389,
  • AI467389,
  • MGI:2140302,
  • 9130020C19Rik,
  • Dph2
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Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

4 Involved In Mutations

Trail: ProteinCodingGene

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For





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