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Protein Coding Gene : Guca2a guanylate cyclase activator 2a (guanylin)

Primary Identifier  MGI:102738 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  14915
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable guanylate cyclase activator activity. Predicted to be located in extracellular region. Is expressed in several structures, including Meckel's cartilage; axial skeleton; esophagus; ganglia; and lower urinary tract. Orthologous to human GUCA2A (guanylate cyclase activator 2A).
PHENOTYPE: Homozygous mutation of this gene results in increased proliferation and migration rate of colonic epithelia. [provided by MGI curators]
  • synonyms:
  • guanylate cyclase activator 2a (guanylin),
  • Guca2,
  • MGD-MRK-19643,
  • Guca2a

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

4 Involved In Mutations

0 Strain

0 Transcripts

1 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

2 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For