| Primary Identifier | MGI:1270851 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 14916 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable guanylate cyclase activator activity. Involved in several processes, including glucose homeostasis; reduction of food intake in response to dietary excess; and response to glucose. Acts upstream of or within body fluid secretion; negative regulation of blood pressure; and renal sodium ion absorption. Predicted to be located in extracellular region. Orthologous to human GUCA2B (guanylate cyclase activator 2B). PHENOTYPE: Homozygotes for a targeted null mutation exhibit elevated blood pressure, increased sodium levels, and reduced sodium, potassium, and fluid excretion following salt loading. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
