Primary Identifier | MGI:104515 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 12163 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cytokine activity. Involved in osteoblast differentiation. Acts upstream of or within germ cell development and spermatogenesis. Predicted to be active in extracellular space. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and limb. Orthologous to several human genes including BMP8A (bone morphogenetic protein 8a). PHENOTYPE: About half of the males homozygous for targeted mutations of this gene show spermatogenesis defects and germ cell degeneration. [provided by MGI curators] |