| Primary Identifier | MGI:2446630 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 236511 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and miRNA binding activity. Involved in positive regulation of gene expression and positive regulation of non-canonical NF-kappaB signal transduction. Acts upstream of or within miRNA metabolic process and positive regulation of transcription by RNA polymerase II. Located in P-body; cytosol; and nucleus. Part of RISC complex. Is expressed in several structures, including 2-cell stage embryo; central nervous system; lung epithelium; sensory organ; and tooth. Human ortholog(s) of this gene implicated in alcohol dependence. Orthologous to human AGO1 (argonaute RISC component 1). PHENOTYPE: Mice homozygous for a conditional allele activated in keratinocytes exhibit no abnormal phenotype. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
