Primary Identifier | MGI:1347351 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 26562 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in neuron projection development and regulation of postsynaptic neurotransmitter receptor internalization. Acts upstream of or within bone resorption. Located in neuron projection. Is active in glutamatergic synapse and postsynapse. Is expressed in several structures, including central nervous system; dorsal root ganglion; femur; and tendon. Orthologous to human NCDN (neurochondrin). PHENOTYPE: Targeted inactivation of this gene results in early embryonic lethality in the homozygous state and impaired chondrocyte proliferation and differentiation in the heterozygous state. Gene trap mutation resulted in lacrimal gland hypertrophy. [provided by MGI curators] |