| Primary Identifier | MGI:87978 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 11637 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable adenylate kinase activity. Predicted to contribute to nucleobase-containing compound kinase activity. Predicted to be involved in ADP biosynthetic process; AMP metabolic process; and dATP metabolic process. Located in sperm mitochondrial sheath. Is expressed in several structures, including alimentary system; brain; genitourinary system; musculoskeletal system; and sensory organ. Human ortholog(s) of this gene implicated in reticular dysgenesis. Orthologous to human AK2 (adenylate kinase 2). PHENOTYPE: Mice homozygous for a null allele exhibit embryonic lethality around E7.5 and show severely disrupted and disorganized mitochondria and cristae. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
