|  Help  |  About  |  Contact Us

Protein Coding Gene : Rnf19b ring finger protein 19B

Primary Identifier  MGI:1922484 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  75234
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable ubiquitin binding activity; ubiquitin conjugating enzyme binding activity; and ubiquitin protein ligase activity. Acts upstream of or within natural killer cell mediated cytotoxicity. Located in cytolytic granule. Is expressed in cerebral cortex ventricular layer and cortical plate. Orthologous to human RNF19B (ring finger protein 19B).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired NK cell cytolysis and an impaired ability to control introduced tumor cells. [provided by MGI curators]
  • synonyms:
  • Rnf19b,
  • Ibrdc3,
  • RIKEN cDNA 4930555L03 gene,
  • IBR domain containing 3,
  • RIKEN cDNA 4930534K13 gene,
  • 4930534K13Rik,
  • 4930555L03Rik,
  • MGI:1922517,
  • ring finger protein 19B

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

4 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For