Primary Identifier | MGI:1919955 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 619605 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable RNA binding activity and identical protein binding activity. Predicted to be involved in RNA stabilization. Located in nucleolus. Part of cytosolic large ribosomal subunit. Is expressed in central nervous system and sensory organ. Orthologous to human ZCCHC17 (zinc finger CCHC-type containing 17). PHENOTYPE: Specific KO of the short isoform reduces osteogenic differentiation of mesenchymal stem cells and results in early cellular senescence in the embryonic notochord and forelimb bones. [provided by MGI curators] |