| Primary Identifier | MGI:1931749 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 80912 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables mRNA 3'-UTR binding activity. Involved in several processes, including adult locomotory behavior; post-transcriptional regulation of gene expression; and spermatogenesis. Acts upstream of or within post-transcriptional regulation of gene expression. Located in cytoplasm. Is expressed in several structures, including central nervous system; intestine; olfactory epithelium; retina; and testis. Human ortholog(s) of this gene implicated in cerebellar ataxia type 47. Orthologous to human PUM1 (pumilio RNA binding family member 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased testes weight and size, decreased body weight, oligozoospermia, reduced male fertility, increased male germ cell apoptosis and small seminiferous tubules. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
