| Primary Identifier | MGI:1855691 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 53608 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ATP binding activity; MAP kinase kinase kinase activity; and magnesium ion binding activity. Predicted to be involved in JNK cascade; p38MAPK cascade; and protein phosphorylation. Is expressed in heart and vibrissa. Orthologous to human MAP3K6 (mitogen-activated protein kinase kinase kinase 6). PHENOTYPE: Homozygous and heterozygous null mice display an increased incidence of chemically induced skin tumors and homozygous mice also show resistance to induced apoptosis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
