| Primary Identifier | MGI:1890546 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 83557 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables RNA binding activity and translation initiation factor binding activity. Involved in several processes, including RNA metabolic process; cellular response to glucose stimulus; and positive regulation of intracellular signal transduction. Acts upstream of or within several processes, including miRNA metabolic process; negative regulation of glial cell differentiation; and regulation of gene expression. Located in nucleolus and rough endoplasmic reticulum. Is expressed in several structures, including early conceptus; embryo ectoderm; limb primordium; reproductive system; and tooth. Used to study nephroblastoma. Orthologous to human LIN28A (lin-28 homolog A). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased birth weight and postnatal lethality. In another report, mice homozygous for the same or an identical allele exhibit reduced premordial germ cells and fertility. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
