| Primary Identifier | MGI:1888742 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 56219 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity and glucuronosyltransferase activity. Predicted to be involved in heparan sulfate proteoglycan biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in Golgi apparatus. Is expressed in several structures, including cranium; jaw; limb; nose; and sclerotome. Orthologous to human EXTL1 (exostosin like glycosyltransferase 1). PHENOTYPE: Mice with loss of expression in dendritic cells display impaired dendritic cell chemotaxis, increased susceptibility to bacterial infection, and autoimmune disorders in elderly mice. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
