| Primary Identifier | MGI:2429859 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 242700 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cytokine receptor activity. Involved in defense response to virus and mucosal immune response. Predicted to be part of interleukin-28 receptor complex. Predicted to be active in plasma membrane. Is expressed in epidermis; gut; lower urinary tract; sensory organ; and submandibular gland primordium. Orthologous to human IFNLR1 (interferon lambda receptor 1). PHENOTYPE: Homozygous null mice are viable and normal with respect to viral infection, however antiviral response evoked by TLRs are significantly reduced. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
