| Primary Identifier | MGI:1096341 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 242705 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription factor activity. Acts upstream of or within several processes, including intrinsic apoptotic signaling pathway by p53 class mediator; lens fiber cell apoptotic process; and regulation of DNA-templated transcription. Located in nucleus. Is expressed in several structures, including alimentary system; cartilage condensation; central nervous system; genitourinary system; and skin. Orthologous to human E2F2 (E2F transcription factor 2). PHENOTYPE: Mice homozygous for a null allele exhibit premature death with signs of inflammatory and autoimmune disorders such as increased memory T cells, enlarged spleen, glomerulonephritis, inflammed liver, inflammed lung, increased double stranded DNA antibodies, hair loss, and erythema. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
