| Primary Identifier | MGI:109378 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 13842 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables GPI-linked ephrin receptor activity and growth factor binding activity. Involved in several processes, including ephrin receptor signaling pathway; neuron development; and positive regulation of intracellular signal transduction. Acts upstream of or within cellular response to follicle-stimulating hormone stimulus. Located in neuron projection and plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human EPHA8 (EPH receptor A8). PHENOTYPE: Mice homozygous for this targeted mutation are viable, fertile, and grossly normal but exhibit a commissural defect, whereby tectal axons fail to project from the superior colliculus of the midbrain to the contralateral inferior colliculus and instead project to the ipsilateral cervical spinal cord. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
