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Protein Coding Gene : Camk2n1 calcium/calmodulin-dependent protein kinase II inhibitor 1

Primary Identifier  MGI:1913509 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  66259
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables protein kinase inhibitor activity. Involved in long-term memory and positive regulation of inflammatory response. Located in postsynaptic density. Is expressed in several structures, including brain; genitourinary system; hemolymphoid system gland; liver; and stomach. Human ortholog(s) of this gene implicated in ovarian cancer; ovarian carcinoma; and prostate adenocarcinoma. Orthologous to human CAMK2N1 (calcium/calmodulin dependent protein kinase II inhibitor 1).
PHENOTYPE: Homozygous null mice show exacerbated cardiac dysfunction, larger fibrosis area, higher incidence of premature ventricular contractions and higher susceptibility to ventricular tachycardia or ventricular fibrillation after myocardial infarction. [provided by MGI curators]
  • synonyms:
  • Camk2n1,
  • AI891706,
  • 1810006K23Rik,
  • AI848599,
  • RIKEN cDNA 1810006K23 gene,
  • MGI:2140380,
  • expressed sequence AI848599,
  • expressed sequence AI891706,
  • CaMKIINalpha,
  • MGI:2140403,
  • calcium/calmodulin-dependent protein kinase II inhibitor 1

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For