Primary Identifier | MGI:1349661 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 26971 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables phospholipase A2 activity. Involved in arachidonate metabolic process and phosphatidylethanolamine acyl-chain remodeling. Acts upstream of or within negative regulation of T cell proliferation and phospholipid metabolic process. Predicted to be located in extracellular region and plasma membrane. Is expressed in several structures, including alimentary system; integumental system; nervous system; sensory organ; and urinary system. Orthologous to human PLA2G2F (phospholipase A2 group IIF). PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal IgE antigen-dependent passive cutaneous anaphylaxis. [provided by MGI curators] |