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Protein Coding Gene : Exosc10 exosome component 10

Primary Identifier  MGI:1355322 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  50912
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable 3'-5'-RNA exonuclease activity; single-stranded RNA binding activity; and telomerase RNA binding activity. Acts upstream of or within positive regulation of mRNA cis splicing, via spliceosome. Predicted to be located in cytosol; euchromatin; and nucleoplasm. Predicted to be part of nuclear exosome (RNase complex) and small-subunit processome. Predicted to be active in nucleolus. Is expressed in several structures, including cerebral cortex; gonad; liver; metanephros; and muscle tissue. Orthologous to human EXOSC10 (exosome component 10).
PHENOTYPE: Mice homozygous for a null allele exhibit reduced female fertility with defective GVBD and endomembrane components. [provided by MGI curators]
  • synonyms:
  • RRP6,
  • PM/Scl-100,
  • Pmscl2,
  • p3,
  • p4,
  • p2,
  • exosome component 10,
  • PM-Scl,
  • Exosc10,
  • polymyositis/scleroderma autoantigen 2

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For